WP7_1 - Endocrine response mechanisms, secretion, localisation and function of receptors, and metabolism of the satiety hormones in isolated organs and transgenic mouse models

University of Copenhagen - Faculty of Health Sciences at: Department of Biomedical Sciences
Project leader

For several of the satiety hormones, their mechanism of action seems to involve transmission via vagal sensory afferents. In this project expression of receptors are investigated in the nodose ganglion as well as in the brain stem. Furthermore, this mode of action are investigated for PP, GLP-2 and Ghrelin in pig models of afferent vagus activity.

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DANORC is supported by the
The Danish Council for Strategic Research
Institute of Preventive Medicine
Frederiksberg Hospital
Nordre Fasanvej 57
2000 Frederiksberg
Denmark
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